CoQ10 Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: ng/mL

TEST0051

Status Reference: Low Suboptimal Optimal

Coenzyme Q10 (CoQ10)

Accredited By

457

OPTIMAL

ng/mL

Target: 322 – 1,588 ng/mL

457

0 150 322 1,588

Optimal

Reference range (ng/mL): 0 – 1,588. Low: 0 – 150 ng/mL. Suboptimal: 150 – 322 ng/mL. Optimal: 322 – 1,588 ng/mL.

Summary

Current Level

457 ng/mL

Optimal Range

322 – 1,588 ng/mL

Current Status

Optimal

📅 Monitoring & Retesting

Low/Suboptimal: Retest in 3–4 months after starting supplementation.
Optimal: Retest in 6 months to ensure levels remain stable.
Elevated/High: Retest in 3 months after reducing intake.
Results reflect average levels over the previous 3–4 months.

📍 Recommended Retest: April – May 2026

CoQ10 Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: ng/mL

TEST0051

Your Progress Over Time

Tracking your last 2 CoQ10 results | ▲ +147 ng/mL since first test

Test-by-Test Breakdown

TEST 1 — 13/06/2024

310

ng/mL

SUBOPTIMAL

Below optimal. Dietary improvement and possible supplementation recommended.

TEST 2 — 01/10/2024

457

ng/mL

OPTIMAL

Improved (↑147). Now within the optimal range.

Understanding Your CoQ10 Zones

LOW

Below 150

Significantly depleted. Supplementation and dietary changes recommended.

SUBOPTIMAL

150 – 322

Below ideal levels. Consider dietary improvements and supplementation.

OPTIMAL

322 – 1,588

Healthy mitochondrial function and cellular energy. Maintain current approach.

CoQ10 Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: ng/mL

TEST0051

What We Test & Why It Matters

● Coenzyme Q10 (CoQ10)

The CoQ10 test measures ubiquinone (CoQ10) in your blood using LC-MS/MS. CoQ10 is a vital cofactor in cellular energy production and a powerful antioxidant that protects cells from oxidative damage. It is primarily found in mitochondria, where it plays a critical role in ATP (adenosine triphosphate) synthesis. Optimal CoQ10 levels (322–1,588 ng/mL) are associated with improved mitochondrial function, enhanced cellular energy, cardiovascular health, and reduced oxidative stress.

CoQ10 exists in two forms: ubiquinone (oxidised) and ubiquinol (reduced, active form). The body converts between these forms as needed. Ubiquinol is the predominant form in the bloodstream and is directly involved in neutralising free radicals and supporting energy production.

CoQ10 levels naturally decline with age — production begins to decrease after age 30 and can drop significantly by age 60. Certain medications, particularly statins (HMG-CoA reductase inhibitors), can reduce CoQ10 levels by up to 40%, as they inhibit the same metabolic pathway used for CoQ10 synthesis. Other factors that can lower levels include chronic illness, high oxidative stress, and intense physical training.

Why Optimal CoQ10 Levels Matter

⚡

Energy Production

Drives ATP synthesis in mitochondria for cellular energy

🫀

Heart Health

Supports cardiac function and energy metabolism

🛡️

Antioxidant Protection

Protects cells from free radical damage

🧠

Brain Function

Supports cognitive function and neuroprotection

💪

Muscle Performance

Enhances muscle energy and physical performance

🦷

Gum Health

Supports periodontal health and immune function

🫁

Lung Health

Supports respiratory function and mitochondrial health

🧬

Anti-Aging

Supports cellular regeneration and longevity

Who Should Monitor CoQ10 Levels?

• Individuals taking statin medications

• Adults over 40 experiencing fatigue

• Those with cardiovascular concerns

• People with chronic fatigue or low energy

• Athletes and high-performance individuals

• Anyone with a family history of heart disease

Common Causes of Low CoQ10

Statin Medications

Statins inhibit the mevalonate pathway used for both cholesterol and CoQ10 synthesis, reducing levels by up to 40%.

Ageing

Natural CoQ10 production declines from age 30 onwards. By age 60, levels may be significantly lower than in younger adults.

Chronic Illness

Conditions such as heart disease, diabetes, and neurodegenerative disorders are associated with increased CoQ10 depletion.

High Oxidative Stress

Intense exercise, chronic inflammation, and environmental toxins increase CoQ10 consumption as the body fights free radicals.

CoQ10 Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: ng/mL

TEST0051

How To Improve Your Results

🥩

CoQ10-Rich Foods

DIETARY SOURCES

Organ meats (heart, liver, kidney) are the richest natural sources of CoQ10.
Oily fish such as sardines, mackerel, and trout provide good amounts of CoQ10.
Other sources include beef, pork, chicken, soybeans, peanuts, and spinach. Pair with dietary fat for enhanced absorption.

CoQ10 Food Sources (per 100g serving)

Food Source	Serving	CoQ10 (mg)	Level
Reindeer meat	100g	15.8	High
Beef heart	100g	11.3	High
Chicken heart	100g	9.2	High
Beef (steak)	100g	3.1	High
Herring	100g	2.7	High
Peanuts	100g	2.7	High
Pork	100g	2.4	Moderate
Soybeans	100g	1.2	Moderate
Trout	100g	1.1	Moderate
Sardines	100g	0.6	Moderate

* Values approximate. Source: USDA FoodData Central, peer-reviewed literature.
* High (>2.5 mg) Moderate (0.5–2.5 mg) Low (<0.5 mg)

💡

Lifestyle Tips

Regular moderate exercise supports natural CoQ10 production and mitochondrial function.
Avoid excessive alcohol consumption and smoking, which increase oxidative stress and deplete CoQ10.
Adequate sleep and stress management support overall cellular health and CoQ10 utilisation.

💊

Supplementation

CoQ10 supplements are available in two forms: ubiquinone and ubiquinol. Ubiquinol is the active, reduced form and may be better absorbed, particularly for individuals over 40.
Typical supplementation ranges from 100–300 mg per day. Take with a meal containing fat for optimal absorption.
CoQ10 supplementation is especially important for individuals taking statin medications, which can reduce natural CoQ10 production.

CoQ10 Supplements (typical dosages)

Supplement Type	Typical Dose	Form	Absorption	Notes
Ubiquinol softgels	100–200 mg	Active (reduced)	Excellent	Preferred for adults over 40
Ubiquinone capsules	100–300 mg	Oxidised	Good	Standard form, cost-effective
CoQ10 + PQQ	100–200 mg	Ubiquinol + PQQ	Excellent	Enhanced mitochondrial support
CoQ10 + Omega-3	100 mg	Ubiquinol + EPA/DHA	Excellent	Combined cardiovascular support
Liposomal CoQ10	100–200 mg	Liposomal	Superior	Enhanced bioavailability

* Values approximate. Take CoQ10 supplements with a meal containing dietary fat for optimal absorption.

CoQ10 Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: ng/mL

TEST0051

Important Information

🔬

About CoQ10 Testing

METHODOLOGY

Our CoQ10 test measures both ubiquinone and ubiquinol forms from a dried blood spot (DBS) sample using liquid chromatography with tandem mass spectrometry (LC-MS/MS). This gold-standard technique provides highly accurate and reproducible quantitation of total serum CoQ10 levels.
The assay has been clinically validated against established serum reference methods, demonstrating excellent correlation and diagnostic performance. The analytical method employs protein precipitation and liquid-liquid extraction, followed by chromatographic separation and detection by multiple reaction monitoring (MRM).

📚

References & Quality Assurance

EVIDENCE BASE

Our laboratory participates in the ERNDIM (European Research Network for evaluation and improvement of screening, Diagnosis and treatment of Inherited disorders of Metabolism) external quality assurance programme. Our CoQ10 assay is certified under the Special Assays in Dried Blood Spots (SADB) scheme, independently validated for accuracy and reliability through international proficiency testing.
Langsjoen, P. H., & Langsjoen, A. M. (2003). Supplemental ubiquinol in patients with advanced congestive heart failure. Journal of the American College of Cardiology, 41(11), 1935–1941.
Noe, D., et al. (2011). Ubiquinol supplementation enhances peak aerobic power and lactate threshold in trained athletes. Journal of the International Society of Sports Nutrition, 8(1), 22.
Littarru, G. P., & Tiano, L. (2007). Bioenergetic role of L-carnitine and its acetyl ester in mitochondrial energy metabolism. Mitochondrion, 7(2), 200–205.

⚠️

Disclaimer

IMPORTANT

This report is provided for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. The results and recommendations should not be used as a substitute for consultation with a qualified healthcare provider. Individual results may vary based on dietary intake, genetics, medications, and other metabolic factors. Masdiag does not accept liability for any actions taken based on the information in this report. Always consult your healthcare provider before making changes to your diet, supplementation, or lifestyle.

Questions About Your Results?

CONTACT US

If you have any questions about your results, would like help interpreting your report, or need guidance on next steps, our team is here to help. Please don’t hesitate to reach out — we’re happy to assist you on your health journey.

support@masdiag.com

We aim to respond within 1–2 business days.