Glutathione Index Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: Index

TEST0051

Status Reference: Low Suboptimal Optimal

Glutathione Index

920

OPTIMAL

Index

Target: 800 – 2,800
Indicates antioxidant capacity and redox balance

(Based on your current level)

920

0 500 800 2,800

Optimal

Summary

Current Level

920 Index

Whole blood glutathione

Optimal Range

800 – 2,800 Index

Target for healthy adults

Current Status

Optimal

Within desirable range

📅 Monitoring & Retesting

Low/Suboptimal: Retest in 3–4 months after starting supplementation.
Optimal: Retest in 6 months to ensure levels remain stable.
Elevated/High: Retest in 3 months after reducing intake.
Results reflect average levels over the previous 3–4 months.

📍 Recommended Retest: April – May 2026

Glutathione Index Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: Index

TEST0051

What We Test & Why It Matters

Tracking your last 2 Glutathione Index results | ▲ +270 since first test

Test-by-Test Breakdown

TEST 1 — 15/08/2025

650

Index

SUBOPTIMAL

Below optimal. Dietary improvement and supplementation recommended.

TEST 2 — 01/01/2026

920

Index

OPTIMAL

Improved (↑270). Now within the optimal range.

Understanding Your Glutathione Index Zones

LOW

Below 500

Depleted antioxidant reserves. Supplementation and dietary changes recommended.

SUBOPTIMAL

500 – 800

Approaching sufficiency but below ideal. Dietary and lifestyle adjustments advised.

OPTIMAL

800 – 2,800

Strong antioxidant capacity and healthy redox balance. Maintain current approach.

Glutathione Index Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: Index

TEST0051

What We Test & Why It Matters

● Glutathione

Glutathione is the body’s most abundant and important intracellular antioxidant. The Glutathione Index measures your overall glutathione status from a dried blood spot sample using LC-MS/MS, reflecting your body’s antioxidant capacity and redox balance.

Glutathione plays a critical role in detoxification, immune function, and protecting cells from oxidative damage. It is synthesised from three amino acids: cysteine, glycine, and glutamic acid. Levels can be influenced by age, diet, toxin exposure, medications, chronic illness, and lifestyle factors such as exercise and sleep quality.

Low glutathione levels have been linked to increased susceptibility to infections, accelerated aging, liver dysfunction, neurodegenerative conditions, and a higher risk of chronic diseases. Maintaining optimal glutathione levels is one of the most important strategies for long-term cellular health and resilience against environmental and metabolic stressors.

Glutathione exists in two forms: reduced glutathione (GSH), which is the active form that directly neutralises free radicals and toxins, and oxidised glutathione (GSSG), which is produced after GSH performs its protective function. A healthy body continuously recycles GSSG back to GSH through the enzyme glutathione reductase. The Glutathione Index captures both forms to give a comprehensive picture of your antioxidant reserves and your body’s ability to cope with oxidative challenges from pollution, stress, illness, and ageing.

Why Optimal Glutathione Levels Matter

🦠

Detoxification

Neutralises toxins, heavy metals, and harmful metabolites

⚡

Antioxidant Defence

Master antioxidant protecting cells from oxidative damage

🧬

DNA Repair

Supports DNA synthesis and protects against mutations

🛡️

Immune Function

Fuels immune cells and supports pathogen defence

🧠

Brain Health

Protects neurons from oxidative stress and neurodegeneration

🫁

Lung Health

Critical for respiratory defence and airway protection

🫀

Heart Health

Reduces oxidative damage to blood vessels and heart tissue

⏳

Healthy Ageing

Slows cellular ageing by reducing oxidative stress

Common Causes of Low Glutathione

Poor Diet

Insufficient intake of sulfur-rich foods (cruciferous vegetables, garlic, onions, whey protein) limits the body's ability to synthesise glutathione.

Chronic Oxidative Stress

Pollution, smoking, alcohol, and chronic inflammation consume glutathione faster than the body can replenish it.

Ageing

Glutathione production naturally declines with age, contributing to increased oxidative damage and reduced detoxification capacity.

Liver Conditions

The liver is the primary site of glutathione synthesis. Conditions like fatty liver, hepatitis, or cirrhosis impair production significantly.

Glutathione Index Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: Index

TEST0051

How To Improve Your Results

🥕

Dietary Sources

Eat liver (beef or chicken) once per week — it is the richest natural source of glutathione (glutathione).
Include orange and yellow vegetables (sweet potato, carrots, pumpkin) and dark leafy greens (spinach, kale) regularly. These are rich in glutathione precursor, which your body converts to Glutathione.
Include egg yolks, dairy products (milk, cheese, butter), and fortified cereals in your diet.
Note: glutathione precursor absorption is enhanced by dietary fat — cook vegetables with a small amount of oil or butter.

Glutathione-Boosting Foods (key dietary sources)

Food Source	Serving	Key Nutrient	Benefit
Broccoli	100g	Sulforaphane	HIGH
Brussels Sprouts	100g	Sulforaphane	HIGH
Garlic	3 cloves	Allicin / Sulfur	HIGH
Onions	100g	Quercetin / Sulfur	MODERATE
Spinach	100g	Folate / Glutathione	HIGH
Avocado	1 medium	Glutathione	HIGH
Asparagus	100g	Glutathione	HIGH
Whey Protein	30g	Cysteine	HIGH
Eggs	2 large	Cysteine / Selenium	MODERATE
Turmeric	1 tsp	Curcumin	MODERATE

* Ratings based on concentration of glutathione precursors and sulfur compounds. Source: Peer-reviewed nutritional literature. High Moderate

💡

Lifestyle Tips

Combine plant sources of Glutathione (glutathione precursor) with dietary fat for better absorption. Cooking vegetables also improves glutathione precursor bioavailability.
Avoid excessive alcohol consumption, as it impairs Glutathione metabolism and storage in the liver.
Smokers may have lower Glutathione Indexs — maintaining adequate intake through diet is especially important.

💊

Supplementation

N-Acetylcysteine (NAC) is one of the most effective precursors for boosting glutathione. Typical dosages range from 600–1,200 mg per day.
Liposomal glutathione supplements provide enhanced bioavailability and are better absorbed than standard oral glutathione.
Alpha-lipoic acid, selenium, vitamin C, and vitamin E support glutathione recycling and overall antioxidant status.

Glutathione Supplements (typical dosages)

Supplement Type	Typical Dose	Form	Absorption	Notes
Liposomal Glutathione	250–500 mg	Liposomal	Superior	Best oral bioavailability
Reduced Glutathione (GSH)	250–500 mg	Capsule	Moderate	Standard supplemental form
N-Acetylcysteine (NAC)	600–1,200 mg	Capsule	Good	Key precursor for glutathione synthesis
Alpha-Lipoic Acid	300–600 mg	Capsule	Good	Helps recycle glutathione
Milk Thistle (Silymarin)	150–300 mg	Extract	Good	Supports liver glutathione levels

* Values are approximate and may vary by product and individual. Consult a healthcare professional before starting any supplementation.

Glutathione Index Report

Referral: ABC Clinic

Name: Sarah Mitchell

DOB: 01/01/2000

Collection Date: 01/01/2026

Received Date: 05/01/2026

Report Date: 08/01/2026

Sample Type: Dried Blood Spot

Analysis: LC-MS/MS

Measurement Unit: Index

TEST0051

Important Information

🔬

About Glutathione Index Testing

METHODOLOGY

Our Glutathione Index test measures both reduced glutathione (GSH) and oxidised glutathione (GSSG) from a capillary dried blood spot (DBS) sample using liquid chromatography with tandem mass spectrometry (LC-MS/MS). While GSH and GSSG are individually quantified in µmol/L, the results are combined and reported as a single Glutathione Index value, providing a comprehensive assessment of your overall glutathione status and redox balance.
GSH is the active, reduced form responsible for neutralising free radicals and supporting detoxification, while GSSG is the oxidised form produced when glutathione performs its protective function. The ratio and total levels of these two forms provide critical insight into your body’s antioxidant capacity and ability to manage oxidative stress.

📚

References & Quality Assurance

EVIDENCE BASE

Wu, G., et al. (2004). Glutathione metabolism and its implications for health. Journal of Nutrition, 134(3), 489–492.
Richie, J. P., et al. (2015). Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. European Journal of Nutrition, 54(2), 251–263.
Forman, H. J., Zhang, H., & Rinna, A. (2009). Glutathione: overview of its protective roles. Molecular Aspects of Medicine, 30(1–2), 1–12.
Pizzorno, J. (2014). Glutathione! Integrative Medicine, 13(1), 8–12.

⚠️

Disclaimer

IMPORTANT

This report is provided for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. The results and recommendations should not be used as a substitute for consultation with a qualified healthcare provider. Individual results may vary based on dietary intake, genetics, medications, and other metabolic factors. Masdiag does not accept liability for any actions taken based on the information in this report. Always consult your healthcare provider before making changes to your diet, supplementation, or lifestyle.

Questions About Your Results?

CONTACT US

If you have any questions about your results, would like help interpreting your report, or need guidance on next steps, our team is here to help. Please don’t hesitate to reach out — we’re happy to assist you on your health journey.

📧 support@masdiag.com

We aim to respond within 1–2 business days.