Research & Specialist ARG

Arginine Metabolites.

Arginine metabolite profiling from plasma or serum by LC-MS/MS for scientific research on nitric oxide metabolism.

Quick Reference
Method
LC-MS/MS
Sample Types
Plasma / Serum
Analytes

6 metabolites

Turnaround

3–5 working days

Enquire About This Test

What does this test assess?

This research panel quantifies six metabolites of the arginine-nitric oxide pathway, providing insight into endothelial function, nitric oxide bioavailability, and methylarginine-mediated cardiovascular risk.

Clinical indications include:

  • Research on endothelial dysfunction and nitric oxide bioavailability
  • Investigation of ADMA as cardiovascular risk marker
  • Studies on arginine metabolism in critical illness
  • Urea cycle disorder research
  • Pulmonary hypertension research

Measured analytes

Analyte coverage

Arginine, citrulline, ornithine, methylarginine, asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA).

Analytical technique

All six analytes are quantified simultaneously by isotope-dilution LC-MS/MS from plasma or serum.

Testing process

From enquiry to results — a straightforward process.

1
Get in touch
Contact us to discuss your testing requirements
2
Collect your sample
Blood sample collected by a healthcare professional via standard venepuncture
3
Post to our lab
Samples shipped to our laboratory following standard pre-analytical protocols
4
Receive results
Results delivered within 3–5 working days of sample receipt

Where this test is available

This test is available to healthcare professionals, wellness brands, clinics, and research institutions worldwide. We currently serve partners in:

  • Europe (EU & non-EU)
  • United Kingdom
  • Asia & Southeast Asia
  • Australia & New Zealand
  • United States

Whether you need testing services for your patients, white-label kits for your brand, or method transfer to your own laboratory — get in touch to discuss how we can work together.

Frequently Asked Questions

What does the arginine metabolites test measure?

This test quantifies arginine, ADMA (asymmetric dimethylarginine), SDMA, citrulline, ornithine, and homoarginine — the key players in nitric oxide metabolism.

Why is ADMA clinically important?

ADMA is an endogenous inhibitor of nitric oxide synthase. Elevated ADMA is an independent cardiovascular risk factor, associated with endothelial dysfunction, hypertension, and atherosclerosis.

How is the sample collected?

Venous blood draw into plasma or serum tubes by a healthcare professional.

How long does it take to get results?

Results are typically delivered within 3 to 5 working days from the time your sample arrives at our laboratory. The analysis is performed by LC-MS/MS.

Who should consider this test?

Researchers studying cardiovascular risk, clinicians investigating endothelial dysfunction, and those studying nitric oxide pathway disruption in conditions like preeclampsia and chronic kidney disease.

Which countries is this test available in?

Masdiag's arginine metabolites test is available worldwide through our partner network. We currently serve healthcare professionals, wellness brands, and clinics in Europe, the United Kingdom, Asia, Australia, New Zealand, and the United States. Contact us to discuss testing services, white-label kits, or method transfer to your laboratory.

Interested in this method?

Whether you need testing services, method transfer, or white-label kit development — we'd love to hear from you.