Immunology BORRELIA

Borrelia (Lyme Disease).

Borrelia IgM and IgG antibody detection from DBS by ELISA (EUROIMMUN). Lyme disease clinical diagnosis.

Quick Reference
Method
ELISA
Sample Types
DBS
Analytes

IgM + IgG antibodies

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What does this test assess?

This method detects IgM and IgG antibodies against Borrelia burgdorferi sensu lato species from a dried blood spot, supporting the clinical diagnosis of Lyme disease.

Clinical indications include:

  • Clinical diagnosis of suspected Lyme disease
  • Detection of early (IgM) and late (IgG) immune response to Borrelia infection
  • Screening in endemic areas following tick exposure
  • Evaluation of persistent symptoms in patients with suspected late Lyme disease

Measured analytes

Analyte coverage

IgM and IgG antibodies against Borrelia burgdorferi, B. afzelii, and B. garinii using the EUROIMMUN ELISA platform.

Analytical technique

Antibodies are detected using the EUROIMMUN enzyme-linked immunosorbent assay (ELISA) platform, adapted for the DBS matrix. The assay uses recombinant antigens from the three main pathogenic Borrelia species prevalent in Europe and North America.

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