Quantitative GHB determination from whole blood, vitreous fluid, or urine by LC-MS/MS for forensic applications.
This method provides quantitative determination of γ-hydroxybutyric acid (GHB) for forensic and medico-legal applications, supporting investigations by justice and law enforcement agencies.
Clinical indications include:
γ-Hydroxybutyric acid (GHB). Also available from vitreous fluid (aqueous humour) for post-mortem cases where blood may be unreliable.
GHB is quantified by validated forensic LC-MS/MS method with isotope-dilution internal standardisation. The method accounts for endogenous GHB production and post-mortem formation artefacts.
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