Urinary SAICAR and succinyladenosine measurement by LC-MS/MS for diagnosis of purine synthesis defects.
This method detects specific biomarkers for adenylosuccinate lyase (ADSL) deficiency and ATIC deficiency, two rare but clinically significant disorders of de novo purine synthesis.
Clinical indications include:
SAICAR (succinylaminoimidazole carboxamide riboside) and succinyladenosine (S-Ado).
Both analytes are measured simultaneously by LC-MS/MS from a single urine sample, providing high sensitivity and specificity for these rare disorder-specific biomarkers.
Saicar is an important biomarker for diagnosis of adenylosuccinate lyase (adsl) deficiency. Masdiag measures saicar using validated analytical methods to provide clinically actionable results.
Saicar testing is valuable for Diagnosis of adenylosuccinate lyase (ADSL) deficiency, Diagnosis of AICA-ribosiduria (ATIC deficiency). Understanding saicar levels helps inform personalized health optimization and clinical decision-making.
Saicar is measured from blood. Professional collection ensures proper sample handling and accurate results.
This test is recommended for individuals interested in diagnosis of adenylosuccinate lyase (adsl) deficiency. Masdiag saicar testing helps guide personalized supplementation and health optimization strategies based on objective biomarker data.
Saicar results provide insight into your metabolic status and diagnosis of adenylosuccinate lyase (adsl) deficiency. Combined with clinical context, Masdiag results inform evidence-based interventions for personalized health optimization.
Whether you need testing services, method transfer, or white-label kit development — we'd love to hear from you.