THC and THC-COOH detection from DBS by LC-MS/MS. Cannabis use assessment from a finger-prick sample.
This method detects THC and its primary metabolite THC-COOH in dried blood spots, enabling assessment of recent cannabis use or exposure.
Clinical indications include:
THC (Δ9-tetrahydrocannabinol) and THC-COOH (11-nor-9-carboxy-THC, primary inactive metabolite).
Both analytes are measured by isotope-dilution LC-MS/MS from DBS, providing specific and sensitive detection of cannabis use without cross-reactivity with other cannabinoids or interfering substances.
Whether you need testing services, method transfer, or white-label kit development — we'd love to hear from you.