Research & Specialist TRP

Tryptophan Metabolites.

Tryptophan pathway metabolite profiling from plasma or serum by LC-MS/MS for scientific research applications.

Quick Reference
Method
LC-MS/MS
Sample Types
Plasma / Serum
Analytes

7 metabolites

Enquire About This Test

What does this test assess?

This research panel quantifies seven key metabolites of the tryptophan-kynurenine pathway, providing insight into immune activation, neuroinflammation, and serotonin metabolism for scientific research.

Clinical indications include:

  • Research on neuroinflammation and neurodegeneration
  • Investigation of immune activation via IDO/TDO enzyme activity
  • Studies on depression, schizophrenia, and cognitive function
  • Cancer immunology research (immune checkpoint-related)
  • Tryptophan metabolism in inflammatory and autoimmune conditions

Measured analytes

Analyte coverage

7 metabolites including tryptophan, kynurenine, 3-hydroxykynurenine, kynurenic acid, quinolinic acid, anthranilic acid, and picolinic acid.

Analytical technique

All seven metabolites are quantified simultaneously by isotope-dilution LC-MS/MS from plasma or serum, providing the sensitivity required to measure low-abundance metabolites in the kynurenine pathway.

Interested in this method?

Whether you need testing services, method transfer, or white-label kit development — we'd love to hear from you.