Quantitative determination of thyroid-stimulating hormone from a dried blood spot using chemiluminescence immunoassay (CLIA) on the LIAISON platform.
1 analyte
3–5 working days
TSH measurement is the primary screening test for thyroid dysfunction, enabling detection of both hypothyroidism and hyperthyroidism and monitoring of thyroid hormone replacement therapy.
Clinical indications include:
| Analyte / Group | Components | Clinical Significance |
|---|---|---|
| TSH | Thyroid-stimulating hormone (thyrotropin) | Pituitary hormone that regulates thyroid gland function; primary marker of thyroid status |
Thyroid-stimulating hormone (TSH) is produced by the anterior pituitary gland and regulates the production of thyroid hormones T3 and T4. Due to the negative feedback loop between TSH and thyroid hormones, TSH is exquisitely sensitive to changes in thyroid function, making it the most reliable single screening test for thyroid disorders.
Typical adult reference range
Elevated TSH indicates underactive thyroid
Suppressed TSH indicates overactive thyroid
TSH demonstrates a log-linear relationship with free thyroxine (fT4), meaning that small changes in thyroid hormone production result in amplified changes in TSH. This makes TSH abnormalities detectable before overt changes in thyroid hormone levels occur, enabling early detection of subclinical thyroid disease.
Thyroid disorders are among the most common endocrine conditions, affecting approximately 5% of the general population. Hypothyroidism is particularly prevalent in women and increases with age. Early detection and treatment prevent progression to symptomatic disease including fatigue, weight changes, cognitive impairment, and cardiovascular complications.
TSH is measured using the LIAISON chemiluminescence immunoassay (CLIA) platform, adapted for DBS matrix. This automated immunoassay provides high-throughput analysis with excellent sensitivity and precision across the clinically relevant range.
DBS collection enables thyroid screening in remote and home settings. The LIAISON platform provides standardised, automated analysis with established reference ranges for the DBS matrix.
From enquiry to results in a few simple steps — no clinic visit required.
This test is available to healthcare professionals, wellness brands, clinics, and research institutions worldwide. We currently serve partners in:
Whether you need testing services for your patients, white-label kits for your brand, or method transfer to your own laboratory — get in touch to discuss how we can work together.
Thyroid-stimulating hormone produced by the pituitary gland. It's the most sensitive marker for thyroid dysfunction — both hypothyroidism (high TSH) and hyperthyroidism (low TSH).
Convenient at-home screening without a clinic visit. Ideal for monitoring thyroid medication, routine health checks, and initial screening for thyroid symptoms like fatigue, weight changes, or cold intolerance.
Finger-prick onto a DBS card, at home or in clinic.
Results are typically delivered within 3 to 5 working days from the time your sample arrives at our laboratory, measured by CLIA (chemiluminescence immunoassay) on the LIAISON platform.
TSH alone is an excellent screening test. If TSH is abnormal, fT4 helps distinguish between overt and subclinical thyroid disease. Both tests are available from Masdiag using the same DBS sample.
Masdiag's TSH test is available worldwide through our partner network. We currently serve healthcare professionals, wellness brands, and clinics in Europe, the United Kingdom, Asia, Australia, New Zealand, and the United States. Contact us to discuss testing services, white-label kits, or method transfer to your laboratory.
Whether you need testing services, method transfer, or white-label kit development — we'd love to hear from you.